Please note that ASD is now largely superseded by CASH which provides the same functionality

What is ASD ?

 ASD(Alternative splicing detector) is a user-friendly software that aims to recognize and detect differential alternative splicing(AS) exons in two samples of RNA-Seq data. Since AS events always have two obvious feature in RNA-Seq data, which are altered junction reads and altered coverage of AS-exons, the algorithm of this software considers these two factors while calculating a combine P-value to investigate whether a AS event is statistically significant or not.

1. Zhou X, et al. Transcriptome analysis of alternative splicing events regulated by SRSF10 reveals position-dependent splicing modulation. Nucleic Acids Res. 2014 Apr;42(6):4019-30.
2. Apoptotic Cell-Derived Extracellular Vesicles Promote Malignancy of Glioblastoma Via Intercellular Transfer of Splicing Factors