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Wei, J. et al. The GARP Complex Is Involved in Intracellular Cholesterol Transport via Targeting NPC2 to Lysosomes. Cell Rep. 2017 Jun;19(13):2823-2835.(IF=8.282)

细胞内胆固醇运输的机制研究-武汉大学

2017-06-03

Li, X. et al. MiR-495 Promotes Senescence of Mesenchymal Stem Cells by Targeting Bmi-1. Cell Physiol Biochem. 2017 Jun;42(2):780-796. (IF=5.104)

MiR-495促进间充质干细胞衰老的机制研究-南京大学医学院附属鼓楼医院

2017-06-03

Zhang E, et al. H3K27 acetylation activated-long non-coding RNA CCAT1 affects cell proliferation and migration by regulating SPRY4 and HOXB13 expression in esophageal squamous cell carcinoma. Nucleic Acids Res.2017 Apr 7;45(6):3086-3101.. (IF=10.162)

食管鳞状细胞癌中lncRNA对细胞增殖和迁移的影响-南京医科大学

2017-04-03

Yan Q, et al. Depletion of Arabidopsis SC35 and SC35-like serine/arginine-rich proteins affects the transcription and splicing of a subset of genes. PLoS Genet. 2017 Mar 8;13(3):e1006663. (IF=6.1)

拟南芥可变剪接研究-中科院植生所

2017-03-03

Chen, R.-C. et al. Integrated analysis of microRNA and mRNA expression profiles in HBx-expressing hepatic cells. World J. Gastroenterol. 2017 Mar ;23(10):1787.(IF=3.365)

Hbx肝炎细胞中miRNA和mRNA表达谱整合分析-中南大学湘雅医院

2017-03-03

Xu, M. et al. Genomic characteristics of pancreatic squamous cell carcinoma, an investigation by using high throughput sequencing after in-solution hybrid capture. Oncotarget. 2017 Feb;8(9):14620-14635. (IF=5.168)

胰腺鳞状细胞癌的基因组特征研究-苏州大学第一附属医院

2017-02-03

Cheng, T.-L. et al. Regulation of mRNA splicing by MeCP2 via epigenetic modifications in the brain. Sci Rep. Sci Rep. 2017 Feb 17;7:42790.  (IF=4.259)

小鼠大脑中的可变剪接调控（采用烈冰自主研发的可变剪接算法ASD）-上海生命科学研究院

2017-02-03

Wu, W. et al. CASH: a constructing comprehensive splice site method for detecting alternative splicing events. Brief Bioinform. 2017 Feb;1-13. doi:10.1093/bib/bbx034 (IF=5.134)

CASH：烈冰自主研发的可变剪接算法再升级

2017-02-03

Wang X, et al. Feedback Activation of Basic Fibroblast Growth Factor Signaling via the Wnt/b-Catenin Pathway in Skin Fibroblasts. Front Pharmacol. 2017 Feb 3;8:32. (IF=4.4)

创面愈合细胞迁移的分子机制-温州医科大学 配图：伤口愈合、缠绷带的身体部位

2017-02-03

Gao Y, et al. Single Cas9 nickase induced generation of NRAMP1 knockin cattle with reduced offtarget effects. Genome Biol. 2017 Feb 1;18(1):13. (IF=9.202)

利用单个核酸酶活性的Cas9n获得低脱靶效应的抗牛结核病奶牛-西北农林科技大学

2017-02-03

Li L, et al. Gene expression signatures for phlegm-dampness constitution of Chinese Medicine. Sci China Life Sci. 2017 Jan;60(1):105-107. (IF=2.297)

中医个性化痰湿体质理论的分子机理-北京中医药大学

2017-01-03

Zhang Y, et al. H/ACA Box Small Nucleolar RNA 7A promotes the Self-Renewal of Human Umbilical Cord Mesenchymal Stem Cells.[J]. Stem Cells. 2017 Jan;35(1):222-235.(IF=5.599)

small RNA-seq揭示SNORA7A能够促进人脐带间充质干细胞的自我更新-第二军医大学

2017-01-03

Ju L, et al. Enhanced expression of Survivin has distinct roles in adipocyte homeostasis. Cell Death Dis. 2017 Jan 5;8(1):e2533.（IF=5.965）

存活素的表达增多在小鼠脂肪代谢平衡中发挥重要作用-上海交大第六附属医院

2017-01-03

Heat Stress Regulates the Expression of Genes at Transcriptional and Post-Transcriptional Levels, Revealed by RNA-seq in Brachypodium distachyon

短柄草在热刺激后的转录及转录后调控机制研究

2017-01-03

Zhao, J., Xu, T., Yin, D., Zhang, B. & Bai, J. The Regulatory Roles of MicroRNA in Effects of 2,2’4,4'-Tetrabromodiphenyl Ether (BDE47) on the Transcriptome of Zebrafish Larvae. PLoS One 2017 Jan;12(1):e0169599. (IF=2.806)

miRNA对斑马鱼幼体的转录调控-同济大学

2017-01-03

Liu Q, et al. Combined transcriptome and metabolome analyses to understand the dynamic responses of rice plants to attack by the rice stem borer Chilo suppressalis (Lepidoptera: Crambidae). BMC Plant Biol. 2016 Dec 7;16(1):259. (IF=3.631)

转录和代谢组联合分析揭秘水稻抗虫反应机理-中国农科院植保所

2016-12-03

Hypermethylation of AKT2 gene is associated with neural-tube defects in fetus.

AKT2超甲基化在人胚胎神经管缺陷疾病中的研究价值

2016-12-03

Chen J, et al. Network analysis-based approach for exploring the potential diagnostic biomarkers of acute myocardial infarction. Front Physiol. 2016 Dec 9;7:615. (IF=4.031)

利用已发表数据鉴定首批急性心肌梗塞诊断标记物-吉林大学

2016-12-03

Yu, R., et al. Expression Profiling of Transcriptome and Its Associated Disease Risk in Yang Deficiency Constitution of Healthy Subjects. Evidence-Based Complementray and Alternative Medicine. 2016. Nov:1493098. (IF=1.74)

RNA测序揭示阳虚体质的转录组表达谱及其相关的疾病-北京中医药大学

2016-11-03

Li, Y. et al. Production of Succinate from Acetate by Metabolically Engineered Escherichia coli. ACS Synthetic Biology Vol 5. 2016 Nov 18;5(11):1299-1307. (IF=5.382)

大肠杆菌生物合成琥珀酸的代谢途径-华东理工大学

2016-11-03
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