科研文献 | 上海烈冰生物医药科技有限公司

文献分类	文献名称	发表期刊	IF	年份	作者/致谢/提及烈冰生物
肿瘤免疫	Non-viral, specifically targeted CAR-T cells achieve high safety and efficacy in B-NHL	Nature	64.8	2022	致谢
肿瘤学	Tumor cell-intrinsic epigenetic dysregulation shapes cancer-associated fibroblasts heterogeneity to metabolically support pancreatic cancer	Cancer Cell	50.3	2024	致谢
神经科学	Anti-BCMA CAR-T therapy in patients with progressive multiple sclerosis	Cell	42.5	2025	致谢
肿瘤学	KMT2C deficiency drives transdifferentiation of double-negative prostate cancer and confer resistance to AR-targeted therapy	Cancer Cell	48.8	2025	致谢
肿瘤学	Antiandrogen treatment induces stromal cell reprogramming to promote castration resistance in prostate cancer	Cancer Cell	50.3	2023	致谢
肿瘤学	Multi-omic profiling of clear cell renal cell carcinoma identifies metabolic reprogramming associated withdisease progression	Nature Genetics	31.8	2024	致谢
肿瘤学	Identification of restrictive molecules involved in oncolytic virotherapy using genome-wide CRISPR screening	Journal of Hematology & Oncology	29.9	2024	致谢
其他疾病	Intestinal CXCR6+ ILC3s migrate to the kidney and exacerbate renal fibrosis via IL-23 receptor signaling enhanced by PD-1 expression	Immunity	32.4	2024	致谢
传染病研究	Systemic immune dysregulation in severe tuberculosis patients revealed by a single-cell transcriptome atlas	Journal of Infection	28.2	2023	致谢
骨科	Single-cell RNA-seq analysis identifies meniscus progenitors and reveals the progression of meniscus degeneration	Annals of the Rheumatic Diseases	27.4	2025	致谢
其他疾病	Customizable virus-like particles deliver CRISPR–Cas9 ribonucleoprotein for effective ocular neovascular and Huntington’s disease gene therapy	Nature Nanotechnology	38.3	2025	致谢
心血管疾病	Targeting VEGF-A/VEGFR2 Y949 Signaling Mediated Vascular Permeability Alleviates Hypoxic Pulmonary Hypertension	Circulation	37.8	2022	助力
免疫学研究	Multiomics analyses reveal a critical role of selenium in controlling T cell differentiation in Crohn’s disease	Immunity	32.4	2021	致谢
肿瘤免疫	Inhibition of tumor cell macropinocytosis driver DHODH reverses immunosuppression and overcomes anti-PD1 resistance	Immunity	26.3	2025	致谢
肿瘤免疫	CARD11 signaling regulates CD8+ T cell tumoricidal function	Nature Immunology	27.6	2025	致谢
肿瘤免疫	Microbiota-shaped neutrophil senescence regulates sexual dimorphism in bladder cancer	Nature Immunology	30.5	2025	致谢
肿瘤免疫	Leucine-tRNA-synthase-2-expressing B cells contribute to colorectal cancer immunoevasion	Immunity	32.4	2022	致谢
肿瘤免疫	The zinc finger protein Miz1 suppresses liver tumorigenesis by restricting hepatocyte-driven macrophage activation and inflammation	Immunity	32.4	2021	助力
骨科	Osteopetrosis-like disorders induced by osteoblast-specific retinoic acid signaling inhibition in mice	Bone Research	14.3	2024	致谢
非模式动物	Sexually Dimorphic Response to Hepatic Injury in Newborn Suffering from Intrauterine Growth Restriction	Advanced Science	15.1	2024	助力

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