科研文献 | 上海烈冰生物医药科技有限公司

文献分类	文献名称	发表期刊	IF	年份	作者/致谢/提及烈冰生物
肿瘤免疫	Non-viral, specifically targeted CAR-T cells achieve high safety and efficacy in B-NHL	Nature	64.8	2022	致谢
肿瘤学	Tumor cell-intrinsic epigenetic dysregulation shapes cancer-associated fibroblasts heterogeneity to metabolically support pancreatic cancer	Cancer Cell	50.3	2024	致谢
神经科学	Anti-BCMA CAR-T therapy in patients with progressive multiple sclerosis	Cell	42.5	2025	致谢
肿瘤学	KMT2C deficiency drives transdifferentiation of double-negative prostate cancer and confer resistance to AR-targeted therapy	Cancer Cell	48.8	2025	致谢
肿瘤学	Antiandrogen treatment induces stromal cell reprogramming to promote castration resistance in prostate cancer	Cancer Cell	50.3	2023	助力
肿瘤学	Multi-omic profiling of clear cell renal cell carcinoma identifies metabolic reprogramming associated withdisease progression	Nature Genetics	31.8	2024	致谢
肿瘤学	Identification of restrictive molecules involved in oncolytic virotherapy using genome-wide CRISPR screening	Journal of Hematology & Oncology	29.9	2024	致谢
其他疾病	Intestinal CXCR6+ ILC3s migrate to the kidney and exacerbate renal fibrosis via IL-23 receptor signaling enhanced by PD-1 expression	Immunity	32.4	2024	致谢
传染病研究	Systemic immune dysregulation in severe tuberculosis patients revealed by a single-cell transcriptome atlas	Journal of Infection	28.2	2023	致谢
骨科	Single-cell RNA-seq analysis identifies meniscus progenitors and reveals the progression of meniscus degeneration	Annals of the Rheumatic Diseases	27.4	2025	致谢
其他疾病	Customizable virus-like particles deliver CRISPR–Cas9 ribonucleoprotein for effective ocular neovascular and Huntington’s disease gene therapy	Nature Nanotechnology	38.3	2025	致谢
心血管疾病	Targeting VEGF-A/VEGFR2 Y949 Signaling Mediated Vascular Permeability Alleviates Hypoxic Pulmonary Hypertension	Circulation	37.8	2022	助力
免疫学研究	Multiomics analyses reveal a critical role of selenium in controlling T cell differentiation in Crohn’s disease	Immunity	32.4	2021	致谢
肿瘤免疫	Inhibition of tumor cell macropinocytosis driver DHODH reverses immunosuppression and overcomes anti-PD1 resistance	Immunity	26.3	2025	致谢
肿瘤免疫	CARD11 signaling regulates CD8+ T cell tumoricidal function	Nature Immunology	27.6	2025	致谢
肿瘤免疫	Microbiota-shaped neutrophil senescence regulates sexual dimorphism in bladder cancer	Nature Immunology	30.5	2025	致谢
肿瘤免疫	Leucine-tRNA-synthase-2-expressing B cells contribute to colorectal cancer immunoevasion	Immunity	32.4	2022	致谢
肿瘤免疫	The zinc finger protein Miz1 suppresses liver tumorigenesis by restricting hepatocyte-driven macrophage activation and inflammation	Immunity	32.4	2021	助力
非模式动物	Sexually Dimorphic Response to Hepatic Injury in Newborn Suffering from Intrauterine Growth Restriction	Advanced Science	15.1	2024	助力
其他疾病	Intra-heterogeneity in transcription and chemoresistant property of leukemia-initiating cells in murine Setd2−/− acute myeloid leukemia	Cancer Communications	20.1	2021	共同作者

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