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单细胞核测序技术是在单细胞水平上发展起来的技术，该技术可将冻存样本直接制核捕获，且依旧保存单细胞测序的高分辨率，能够准确区分细胞异质性，揭示单个细胞的基因结构和基因表达状态。因其对样本包容性高，核测序的出现解决了某些珍贵冻存样本，异形细胞样本无法进行单细胞实验的问题，在心肺疾病，神经发育等领域助力临床治疗和诊断，加速精准医疗时代。
1. 突破性改进制核手段，跳过样本消化步骤，冻存组织直接制核
2. 消除因消化偏好性造成的细胞解离偏差，且保证制核质量远高于上机捕获要求
3. 烈冰全程严格地质量把控，提供从实验设计到分析产出的一站式服务流程
样本类型：
1.冻存组织、培养的细胞系等，一般取黄豆粒大小；
2.-80℃冰箱保存，送样时干冰运输
Zhang, et al. Science Bulletin, 2020 Dec.
注：图为猕猴脑组织细胞亚群鉴定t-SNE图展示
Zhang, et al. Science Bulletin, 2020 Dec.
注：Marker基因的Violin图（左）和bubble plot图（右）
Zhang, et al. Science Bulletin, 2020 Dec.
注：该图为不同细胞亚群间差异基因聚类分析图（Heatmap）
Zhang, et al. Science Bulletin, 2020 Dec.
Zhang, et al. Science Bulletin, 2020 Dec.
Zhang C, et al. J Immunother Cancer, 2021;9:e002312.
注：细胞间状态转换的pesudotime轨迹图（左）和Heatmap图（右）
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